Institutsbibliothek für Biochemie und Molekularbiologie

Table of Contents

Table of Contents

Table of Contents

Table of Contents

Preface . . vii

Chapter I Neuronal Cell Apoptosis . . 1
Chapter II Witnessing the Mechanistic Insights of Neuronal Apoptosis from a Global Transcriptomic View: Comparative Microarray Analysis of Multiple Neurodegenerative Models . . 37
Chapter III Death of Neuronal and Glial Cells Induced by Photodynamic Treatment: Ultrastructural Changes and Signaling Mechanisms . . 79
Chapter IV Cell Death During Cerebellar Development . . 119
Chapter V Fundamental Mechanisms and Implications of Neuronal Apoptosis . . 143
Chapter VI How Can We Prevent Neuronal Apoptosis? . . 167
Chapter VII Neuronal Cell Apoptosis . . 191
Chapter VIII Bcl-2 Homology-3 Domain (BH3)-Only Proteins: Harbingers of Neuronal Demise and Neurodegeneration . . 199

Index . . 233

Preface . . vii

Chapter 1 The Varied Functions of Aurora Kinases A and B in Mitosis and Carcinogenesis . . 1
Chapter 2 New Developments in Chromatin Research: An Epigenetic Perspective . . 29
Chapter 3 Sperm Chromatin Integrity, DNA Fragmentation and Male Fertility . . 59
Chapter 4 The Chromatin State of Pluripotent Stem Cells . . 83
Chapter 5 MITF Meets Chromatin in Melanoma . . 105
Chapter 6 The State of Chromatin as an Integrative Indicator of Cell Stress . . 123
Chapter 7 A Genomics Approach to Analysing DNA Damage and Its Repair throughout Entire Genomes . . 145
Chapter 8 Recent Patent on Revolver-2: A Novel Transposon-Like Gene Useful for Chromosome Tags of Rye . . 161
Chapter 9 The Removal of DNA Damage Is Promoted by the Yeast Global Genome Nucleotide Excision Repir Factor Rad16 . . 177
Chapter 10 Chromatin Condensation in Infertile Sperm . . 195
Chapter 11 Glucocorticoid-Induced Chromatin Remodeling: A Novel Molecular Mechanism of Traumatic Stress . . 211

Index . . 223

Preface . . vii

Chapter I Potassium Channels and Vascular Tone: Structure, Regulation and Function . . 1
Chapter II The Contribution of Lymphocyte Potassium Channels to the Perinatal Regulation of the Immune Response in Mother and Newborn . . 49
Chapter III Mitochondrial Potassium Channel: Features and Physiological Participation . . 69
Chapter IV Slow Potassium Channel Dysfunction in Amyotrophic Lateral Sclerosis and Its In Vivo Evaluation by Threshold Tracking . . 83
Chapter V Plant Mitochondrial Potassium: Channel or Channels? . . 97
Chapter VI Involvement of the Mitochondrial ATP-Sensitive Potassium Channel in the Beneficial Effects of Fasting on the Ischemic-Reperfused Rat Heart . . 119

Index . . 135

Preface to the Series . . v
Preface . . vii
Contributors . . xi

1. In Vivo Functional Brain Imaging Using a Genetically Encoded Ca2+-Sensitive Bioluminescence Reporter, GFP-Aequorin . . 1
2. Ca2+ Imaging in Brain Slices Using Bioluminescent Reporters . . 27
3. Calcium Imaging of Neural Activity in the Olfactory System of Drosophila . . 43
4. Functional Imaging of Antennal Lobe Neurons in Drosophila with Synapto-pHluorin . . 71
5. Performing Electrophysiology and Two-Photon Calcium Imaging in the Adult Drosophila Central Brain During Walking Behavior . . 83
6. In Vivo Optical Recording of Brain Interncuron Activities from a Drosophila Male on a Treadmill . . 103
7. Two-Photon Imaging of Population Activity with Genetically Encoded Calcium Indicators in Living Flies . . 113
8. Engineering and Application of Genetically Encoded Calcium Indicators . . 125
9. Imaging cAMP Dynamics in the Drosophila Brain with the Genetically Encoded Sensor Epac1-Camps . . 149

Index . . 169

Preface . . vii
Biography . . ix
Contributors . . xi
Acknowledgments . . xv

Chapter I Overview of Mesenchymal Stem Cells . . 1
Chapter II Mesenchymal Stem Cell Circulation and Trafficking . . 15
Chapter III Mesenchymal Stem Cell In-Vitro Bone Differentiation and Its Applications . . 33
Chapter IV The Osteoblast Differentiation of Mesenchymal Stem Cells from Human Umbilical Cord Blood and from Human Bone Marrow: A Comparative Study . . 61
Chapter V The Role of Stem Cells, Scaffolds and Bioreactors in Musculoskeletal Tissue Engineering . . 111
Chapter VI Neuroprotective Properties of Mesenchymal Stem Cells . . 121
Chapter VII Nurturing Roles of Mesenchymal Stem Cells in Reducing Deficits in Rodent Models of Huntington's Disease . . 149
Chapter VIII Mesenchymal Stem Cells in Osteoarthritis Therapy: Current Status of Theory, Technology, and Applications . . 163
Chapter IX Periodontal Regeneration and Mesenchymal Stem Cells . . 197
Chapter X Mesenchymal Stem Cells in Pancreatic Islet Transplantation . . 197
Chapter XI Human Placental Stem Cells: Biomedical Potential and Clinical Relevance . . 209
Chapter XII Adipose-Derived Mesenchymal Stem Cells . . 233
Chapter XIII Soft Tissue Regeneration with Human Adipose-Derived Stem Cells . . 233
Chapter XIV Application of Adipose-Derived Stem Cells for Bone and Cartilage Regeneration . . 317
Chapter XV Adipose-Derived Stem Cells for Myocardial Regeneration . . 335
Chapter XVI Mesenchymal Stem Cells and Cardiovascular Repair . . 363
Chapter XVII Mesenchymal Stem Cells and Cancer . . 379
Chapter XVIII Short Communication Tendon Regeneration and Repair: The Role of Mesenchymal Stem Cells . . 405

Index . . 413

Preface . . vii
Chapter I Interferon Regulatory Factors in Immune Cell Development and Host Response to Infections . . 1
Chapter II Interferon-Gamma, Oligodendrocyte Injury and Inflammatory Demyelination . . 67
Chapter III Interferons and Their Effect on NK Cells Activity in HIV Infection and Tumour Cells Development . . 83
Chapter IV Interferons, Serine Proteases and Protease-Activated Receptors: Enemies or Partners? . . 95
Chapter V The Roles of IFN- y in Esophageal Squamous Cell Carcinoma . . 107
Chapter VI Interferons in Multiple Sclerosis: Clinical Applications and Possible Mechanisms of Actions . . 119
Chapter VII Dynamics of Lymphocyte Subpopulations in Patients with Chronic Hepatitis C Virus Infection During Pegylated Interferon-Alpha2a and Ribavirin Treatment . . 129
Chapter VIII Co-Administration of Gamma Interferon Gene with DNA Vaccine Expressing Duck Hepatitis B Virus (DHBV) Proteins Enhances Therapeutic Efficacy of DNA-Based Immunization in Chronic Virus Carriers . . 135
Chapter IX Rabies Virus Evasion of the Interferon System . . 163
Index . . 163